摘要
1例53岁女性患者,因神经衰弱、神经症给予补肾益脑胶囊4粒/次,3次/d口服;艾司唑仑2 mg,睡前口服。连续用药70 d后患者再次出现精神症状,并伴有嗜睡、皮肤及巩膜黄染。肝功能示ALT274 U/L,AST57.0 U/L,TBiL 32.4μmon/L,DBiL19.8μmon/L。尿常规:胆红素(++),尿胆原(++),酮体(+)。停用补肾益脑胶囊,艾司唑仑继续服用,并给于保肝治疗。3周后肝功能恢复正常。
A 53-year-old woman with neurasthenia and neurosis received 4 Bushenyinao capsules thrice daily and estazolam 2 mg at bedtime.After 70 days,her mental symptoms recurred,accompanied by somnolence,yellowish skin and sclera.Liver function revealed the following values： ALT 274 U/L,AST 57.0 U/L,TBiL 32.4 μmol/L,DBiL 19.8 μmol/L and routine urine tests showed bilirubin（＋＋）,urobilinogen（＋＋）,and ketone（＋）.Bushenyinao capsules were stopped,estazolam was continued,and liver-protective treatments were given.Three weeks later,her liver function returned to within normal range.
出处
《药物不良反应杂志》
2009年第6期448-449,共2页
Adverse Drug Reactions Journal
关键词
补肾益脑胶囊
不良反应
肝损害
Bushenyinao capsules
adverse reactions
liver damage
