摘要
目的:了解该地区小儿社区获得性肺炎嗜肺军团菌(Lp)的感染情况。方法:选取14岁以下社区获得性肺炎患儿386例,应用ELISA检测其血清Lp1～6型IgG抗体,应用PCR-荧光探针法检测嗜肺军团菌特异性DNA片段。结果:ELISA-IgG阳性14例,PCR-荧光探针法阳性16例,总阳性数18例,阳性率为4.67%;<1岁0例,1～3岁2例(1.6%),3～7岁9例(9.4%),7～14岁9例(10.4%);6～8月份发病10例(55.6%),9～11月份6例(33.3%),12～5月份2例。结论:嗜肺军团菌在小儿社区获得性肺炎中起着一定的病原学作用,各年龄组感染率不同,随年龄增长感染率增加,多发生在夏秋气温较高的季节。
Objective： To investigate the etiologic effects of legionella pneumoniae （Lp） on community -acquired pneumonia in children in Changchun district. Methods： 386 cases of patients diagnosed as community - acquired pneumonia were enrolled randomly, and the specific IgG in paired serum were detected with ELISA, and DNA fragments in NPA with Fluorescent real - time quantitative PCR （ FQ -PCR） . Results： Of 386 cases, 14 were positive with ELISA and 16 with FQ -PCR. The total positive cases were 18, the positive rate was 4. 67%. There was no positive case in younger than 1 yr old, 2 cases in 1 -3 yr old group （1.6%）, 9 in 3 -7 yr （9. 4% ） and 9 in 7 - 14 yr （10. 4） . 10 cases distributed from Jun. to Aug. and 6 from Sept. to Nov. Conclusion： Legionell pneumoniae has some etiologic effect on community - acquired pneumonia in children in Changchuu, the positive rates are becoming higher with the age growing, and high incidence season is in summer and autumn.
出处
《中国妇幼保健》
CAS
北大核心
2010年第8期1064-1065,共2页
Maternal and Child Health Care of China
关键词
嗜肺军团菌
儿童
社区获得性肺炎
病原学
Legionella pneumoniae
Children
Community - acquired pneumonia
Etiology
