摘要
目的探讨胚胎发育不良性神经上皮肿瘤的临床特点、诊断及治疗。方法回顾性分析4例胚胎发育不良性神经上皮肿瘤的临床资料。肿瘤位于颞叶2例,额叶2例。临床表现为反复癫疒间发作。均行开颅肿瘤切除术,术中在脑电监测下对周边致疒间区给予切除。结果颞叶肿瘤脑电图间歇期及发作期均表现为与肿瘤部位相关的异常放电;额叶肿瘤脑电间歇期亦表现为与肿瘤部位相关的异常放电,而发作期则表现为全头或弥漫性放电。手术均全切除肿瘤,术后病理均为胚胎发育不良神经上皮肿瘤。随访6～15个月,无癫疒间发作,MRI显示肿瘤无复发。结论胚胎发育不良性神经上皮肿瘤经手术切除可治愈,术后不需放疗及化疗。
Objective To investigate the clinial feature, diagnosis and treatment of dysembryoplastic neuroepithelial tumor （DNT）. Methods The clinical data of 4 DNT cases were analyzed retrospectively. The tumor located in temporal lobe in 2 cases and frontal lobe in 2. The clinical feature was recurrent seizures. The tumorectomy was performed and the nearby epileptic zone incised under monitoring by electrocorticography during operation. Results The EEG features of tumor during ictal and interictal period were related to the tumor site in temporal lobe tumor, but during ictal period they were presented with generalized epileptiform pattern or whole-head discharges in frontal lobe tumor. The tumors were totally removed. All tumors were confirmed as DNT histopathologically after operation. During a follow-up period ranged from 6 to 15 months, the patients were of no seizure, and also no tumor recurrence in MRI. Conclusions DNT is a surgically curable tumor. Radiotherapy or chemotherapy is not needed.
出处
《中国微侵袭神经外科杂志》
CAS
北大核心
2010年第2期52-54,共3页
Chinese Journal of Minimally Invasive Neurosurgery
