摘要
左旋西替利嗪二盐酸盐(Levocetirizine dihydrochloride),是西替利嗪R-异构体的二盐酸盐,为高选择性外周H1受体拮抗剂。简述了左旋西替利嗪及其二盐酸盐的合成研究进展,主要介绍了化学拆分法及几条相应的合成路线。
Levocetirizine dihydrochloride is the R-isomer of cetirizine dihydrochloride, it is the highly selective peripheral H1 receptor antagonist. This paper described in summary research progress of levocetirizine dihydrochloride and mainly introduced the chemical resolution and some corresponding synthetic routes.
出处
《化学与生物工程》
CAS
2010年第3期18-22,共5页
Chemistry & Bioengineering
