摘要
目的：了解性激素与子宫肌瘤发病的关系。方法：收集１９９６年３月至１９９６年１２月在我科住院手术治疗的子宫肌瘤患者６７例，其中增生期３１例，分泌期３６例，另设健康妇妇对照７２例，增生期３６例，分泌期３６例。采用放射免疫法测定外周血Ｅ２（雌二醇）、Ｐ（孕酮）、Ｔ（睾酮）、ＦＳＨ（卵泡剌激素）和ＬＨ（黄体生成素）的含量。结果：⑴血清中Ｅ２、Ｐ、ＦＳＨ和ＬＨ含量均随月经周期而变化，Ｅ２和Ｐ变化有显著化差异，Ｔ无周期性变化。⑵研究组激素水平在各个时期均与对照组无明显差异（Ｐ＞０．０５）。结论：子宫肌瘤的发病与外周血Ｅ２、Ｐ、Ｔ、ＦＳＨ的含量关系不大，可能与局部雌、孕激素及其受体含量有关。
Objective:To study the relationships between sex hormones and the onset of hysteromyoma.Methods:The levels of peripheral estradiol(E2), progesterone (P), testoferone (T), follicule-stimulating hormone (FSH) and luteotropic hormone (LH) were measured through radioimmunoassay in 67 patients with hysteromyoma who underwent surgical treatment in our department from March to December in 1996. Among them 31 cases were in the proliferative phase and 36 in the secretory period. In addition, a control group of 72 healthy women was made, half in the proliferative phase and half in the secretory phase.Results:The levels of E2,P,FSH and LH varied from menstrual cycles, with a significant difference in E2 and P, and no periodical change in T. The hormone levels of both groups had no significant difference in either phase(P>0.05).Conclusion:The attack of hysteromyoma has little to do with the peripheral E2, P, T, FSH levels, suggesting its close relation to the localization of estrin, progestogen and their receptors.
出处
《郧阳医学院学报》
1998年第4期194-196,共3页
Journal of Yunyang Medical College
关键词
雌二醇
孕酮
FSH
LH
睾酮
子宫肿瘤
肌瘤
neoplasms,myometrium
estradiol progesterone
FSH
LH
testosterone
