期刊文献+

贵阳地区成人外周血淋巴细胞亚群及活化正常参考值 被引量:6

下载PDF
导出
摘要 目的:对贵阳地区100例健康成人外周血淋巴细胞亚群及活化正常参考值进行调查并建立本实验室相应项目的正常参考范围。方法:采用BD Simultest IMK-Lymphocyte四色试剂盒的荧光抗体和BD活化双色试剂对100例体检健康的成人外周血进行染色,以FACSAria流式细胞仪进行分析,FACSDiva Software软件程序获取数据并分析结果,SPSS软件进行统计。结果:18~64岁健康成人的淋巴细胞亚群相对值正常参考范围为:CD3^+细胞(总T淋巴细胞)为49.41%~79.93%,CD3^+CD19^+细胞(B淋巴细胞)为2.09%~16.05%,CD3^+CD4^+细胞(Th淋巴细胞)为19.56%~45.03%,CD3^+CD8^+细胞(Ts淋巴细胞)为11.96%-38.40%,CD3^+/CD16^+CD56^+细胞(NK细胞)为0.19%~32.05%;活化的CD3^+细胞的相对值为0%~7.33%,活化的CD8^+细胞的相对值为0%~5.63%。女性Th淋巴细胞、活化的CD8^+细胞相对值比男性高(P〈0.05)。结论:不同地域、不同种族健康成人外周血淋巴细胞亚群正常参考值有所不同,各实验室应建立针对本地区人群的相应参考值范围。
出处 《贵阳医学院学报》 CAS 2010年第1期64-65,69,共3页 Journal of Guiyang Medical College
  • 相关文献

参考文献7

二级参考文献22

  • 1肖瑶,姚均,王哲,李宏,王鹏,裴丽健,冯基刚,蒋岩.河南省健康人群外周血T淋巴细胞14种表型正常参考值的建立及意义[J].中国艾滋病性病,2004,10(4):244-246. 被引量:12
  • 2章景杰.自然杀伤细胞对B细胞功能的调节[J].国外医学·免役学分册,1985,8:242-242. 被引量:1
  • 3Rubin 1. A. Karman C C. Fritz Me. et al. Soluble Inter - leukin - 2 Receptors Are Released From Activated Human Lymphoid Ceils In Vitro. J Immunol. 1985,135 : 3172. 被引量:1
  • 4Tomkinson BE, Wagner DK, Nelson DL, Sullivan JL. Activated lymphocytes during acute Epstein- Barr virus infecting.J lmmunol. 1987, 139:3802 - 3807. 被引量:1
  • 5Carol T, Schinlen-bick. Evaluation of TruCOUNT absolute-count tubes for determining CD4 and CD8 cell numbers in human immunodeficiency virus-positive adults[J]. Clinical and Diagnostic Laboratory Immunology, May 2000, 336-343. 被引量:1
  • 6Leslie R. Bisset, Thomas L. Lung, matthis Kaelin. Reference values for peripheral blood lymphocyte phenotypes applicable to the healthy adult population in Switzerland[J]. European Journal of haematology, 2004, 72(3). 被引量:1
  • 7Javier Carbone, Juana Gil. Increased levels of activated subsets of CD4 T cells add to the prognostic value of low CD4 T cell counts in a cohort of HIV-infected drug users [J]. AIDS, 2000, 14:2823-2829. 被引量:1
  • 8Mario Roderer, Stephen C. Dynamics of fine T-cell subsets during HIV disease and after thymic ablation by mediastinal irradiation[J]. Immunology, 1997,9; 389-396. 被引量:1
  • 9Janis V. Giorgi, Hong-Nerng Ho. CD8 lymphocyte activation at human immunodeficiency virus type 1 serocnversion: development of levels[J]. The Journal of infection diseases, 1994, 170: 775-781. 被引量:1
  • 10LANDAY A, OHLSSORR WILHELM B, GIORGI J V. Application of flow cytometry to the study of HIV infection [J]. AIDS, 1990, 4: 479-497. 被引量:1

共引文献121

同被引文献57

  • 1杨碧锋,卓广超,周劲峰,冷建杭.学龄前儿童外周血淋巴细胞亚群特点分析[J].浙江临床医学,2004,6(8):699-700. 被引量:6
  • 2肖瑶,姚均,王哲,李宏,王鹏,裴丽健,冯基刚,蒋岩.河南省健康人群外周血T淋巴细胞14种表型正常参考值的建立及意义[J].中国艾滋病性病,2004,10(4):244-246. 被引量:12
  • 3国家SARS防治紧急科技行动北京组,王辰,夏成青.传染性非典型肺炎患者外周血CD4+T细胞CD38的表达及意义[J].中华检验医学杂志,2005,28(8):809-812. 被引量:2
  • 4Parodi JC,Palmaz JC,Barone HD.Transfemeral intraluminal graft implantation for abdominal aortic aneurysms[J].AnnVasc Surg,1991(6):491-499. 被引量:1
  • 5Kam KM,Leung WL,Kwok MY,et al.Lymphocyte subpopulation reference ranges for monitoring human immunodeficiency virus-infected chinese adults[J].Clin Diagn Lab Immunol,1996,3:326-330. 被引量:1
  • 6Reichert TA,De Bruyere M,Dencys V,et al.Lymphocyte subset reference ranges in adult caucasians[J].Clin Immunol Immunolopathol,1991,60:190-207. 被引量:1
  • 7Hughes J.A review of CD4 monitoring by flow cytometry[J].Current Allergy & Clinical Immunology,2003,16(2):61-66. 被引量:1
  • 8Smyth MJ,Thia KY,Street SE,et al.Differential tumor surveillance by natural killer (NK) and NKT cells[J].J Exp Med,2000,191(4):661-668. 被引量:1
  • 9Seki,S,Habu Y,Kawamura T,et al.The liver as a crucial organ in the first line of host defense:the roles of Kupffer cells,natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses[J].Immunol Rev,2000,174:35-46. 被引量:1
  • 10Prince HE,Hirji K,Waldbeser LS,et al.Influence of racial background on the distribution of T-cell subsets and Leu 11-positive lymphocytes in healthy blood donors[J].Diagn Immunol,1985,3(1):33-37. 被引量:1

引证文献6

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部