摘要
目的:探讨ACEI类药物对肾病综合征的治疗作用。方法:将80例患者随机均分为二组,对照组仅用泼尼松和环磷酰胺治疗,治疗组在此基础上给予依那普利。结果:8周后两组的24h尿蛋白量降低,白蛋白升高,甘油三酯和总胆固醇降低,血肌酐降低,但治疗组降低的幅度更大(P<0.05),12周后治疗组的24小时尿蛋白、胆固醇、血肌酐进一步降低(P<0.05),而对照组仅24小时尿蛋白进一步降低,其他改变无统计学差异。结论:以依那普利为代表的ACEI类药物可有效改善肾病综合征的临床症状,且用药8周即有显效,继续用药可进一步发挥作用。
Observe： To observe effect of ACEI class of drugs on the therapeutic nephrotic syndrome.Mehtod： 80 cases of therapeutic nephrotie syndrome derided into tow groups.The control group only gave prednisone and cyclophosphamide treatment while the treatment group given enalapril treatment on this basis, and compaired their urine protein, serum albumin and serum ereatinine after 8 weeks and 12 weeks treatment.Conclusion： ACEI class of drugs can effectively improve the clinical symptoms of nephrotic syndrome.There＇s significant effect after 8 weeks treatment and it could last long. However clinical applications need to master the ACEI class indications and contraindications.
出处
《中国民族民间医药》
2010年第2期116-117,共2页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
肾病综合征
ACEI
herapeutic nephrotic syndrome
ACEI
