摘要
目的:研究糖化血红蛋白A1c(HbA1c)水平与冠心病及其严重程度的关系及意义。方法:对疑诊为冠状动脉粥样硬化性心脏病(冠心病)而做选择性冠状动脉造影的140例患者进行HbA1c测定,采用冠脉狭窄程度积分(Gensini法)和冠脉病变支数分组,评价HbA1c水平与冠心病、冠脉狭窄程度积分及冠脉狭窄支数的相关性。结果:冠心病组患者A1c水平较对照组明显升高(P(0.01),在冠心病组中,HbA1c水平随着冠脉病变支数和Gensini积分的增加而升高。直线相关分析表明:Gensini积分与A1c水平呈正相关(r=0.528,P(0.01)。结果:HbA1c水平与冠脉病变程度呈正相关,HbA1c水平升高是冠心病的危险因素。
Objective：To explore the correlation between the level of glycosylated hemoglobin A1c（HbA1c）and the extent of coronary lesions in coronary heart disease（CHD）.Methods：A total of 140 admitted patients were studied retrospectively.All patients were suspeced to have coronary heart disease and underwent a selective coronary angiography and a survey of HbA1c concentrations during the hospitalization.Results：HbA1c cconcentrations in the patients of the CHD group were significantly higher than that in the patients of the control group（P﹤0.01）.HbA1c concentrations increased with the increasing number of diseased coronary branches and Gensini＇s score in CHD patients.Gensini＇s score was positively correlated with HbA1c concentrations in CHD patients（r=0.528,P﹤0.01）.Conclusion：The level of HbA1c was positively correlated with the coronary artery narrow degree in CHD patients and HbA1c is the risk factor of CHD.
出处
《牡丹江医学院学报》
2010年第1期13-16,共4页
Journal of Mudanjiang Medical University
基金
江西省九江市科技局立项课题[2008]48号
关键词
糖化血红蛋白A1C
冠心病
冠脉狭窄程度积分
glycosylated hemoglobin A1c
coronary heart disease
Gensini＇s degree integral
