摘要
高血糖是最重要的心血管系统危险因素之一,对患者预后具有显著的不良影响。冠心病糖耐量异常患者与与高胰岛素血症、胰岛素抵抗、内皮素、餐后高血糖、糖化终末产物、炎症因子、凝血系统、HbAlC、微量蛋白尿、尿白蛋白排泄率水平相关。导致冠状动脉病变,加重心肌细胞损伤,引起左心室结构与舒张功能明显降低,并与其它各种危险因素相互作用,使猝死及发生充血性心力衰竭的危险性显著增高,促进疾病的发生发展。对冠心病合并糖耐量异常患者进行一般治疗、药物治疗及中医治疗等干预措施,可以最大限度改善患者的预后,具有重要意义。
Hyperglycemia is one of the most dangerous factors of coronary system and has significantly harmful effects on patient＇ s prognosis. Abnormal glucose tolerance of patients with coronary heart disease is associatedwith hyperinsulinemia, insulin resistance, endothelin, postprandial hyperglycemia, glycosylation end products, inflammatory factor, coagulation system, HbAlc, low level proteinuria, and microalbuminuria excretion rate. It willlead to coronary artery pathological changes, worsen damage of heart muscle cells, greatly change the structure and destroy the function of aortic ventricle. If combined with other dangerous factors, it will remarkably increase therisk of sudden death and congestive heart failure. To treat patients with coronary heart disease combined with abnormal glucose tolerance will improve the prognosis.
出处
《辽东学院学报（自然科学版）》
CAS
2011年第4期281-286,共6页
Journal of Eastern Liaoning University:Natural Science Edition
关键词
冠心病
糖耐量异常
临床特点
临床治疗
coronary heart disease
abnormal glucose tolerance
clinical characteristic
clinical treatment
