摘要
[目的]分析肾脏替代治疗对挤压综合征患者伤口的影响,为今后治疗挤压综合征以及制定治疗策略提供更好的临床依据。[方法]收集汶川地震中本院收治的挤压综合征患者临床资料和相关治疗结果,将入选的患者分成肾脏替代治疗组和非肾脏替代治疗组,对比分析伤口感染率、伤口活动性动脉出血发生率、小腿减压切口渗液量的差异。[结果]肾脏替代治疗组和非肾脏替代治疗的伤口感染率差异有统计学意义(P=0.006)。肾脏替代治疗组培养出的致病菌前3位依次是不动杆菌属、铜绿假单胞菌和肠杆菌属,为多重耐药菌株。肾脏替代治疗组创面渗液量显著高于非肾脏替代治疗组(P=0.000)。[结论]肾脏替代治疗易导致挤压综合征患者开放创面渗液量增多、感染率高以及多重耐药菌株混合感染。
[ Objective ] To analyze the effect of renal replacement therapy on the wound of crush syndrome patients, and to provide better clinic evidence for scheduling the therapy strategy of crush syndrome. [ Method] The clinic data of patients suffering from crush syndrome during Wenchuan earthquake were collected and classified into Group A treated by renal replacement therapy and Group B theraped by other treatments except renal replacement therapy. Wound infection rate, wound active artery bleeding occurrence, and the volume of oozes in fasciotomy wound between these two groups were compared. [ Result] There was statistically significant difference in the rate of wound infection between Group A and Group B （ P = 0.006）. The most common pathogens were acinetobacter spp, pseudomonas aeruginosa, and enterobacter spp in Group A, and these pathogens were all multi drug-resistant. There was statistically significant difference in the volume of oozes in incisive wound between these two groups （P = 0. 000） . [ Conchlsion] Renal replacement therapy would increase the volume of oozes, raise the rate of wound infection, and be susceptiblely infected by multi drug-resistant pathogen.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2010年第2期113-116,共4页
Orthopedic Journal of China
关键词
地震
挤压综合征
急性肾衰竭
肾脏替代治疗
伤口感染
earthquake
crush syndrome
acute renal failure
renal replacement therapy
wound infection
