摘要
动态增强MRI可通过小分子钆对比剂无创地对组织血管特征进行评价,获得组织的血流灌注、微血管渗透性和细胞外的漏出间隙等参数。前列腺癌的血管生成是肿瘤的发生、进展、转移的重要因素之一。本文综述两种MR动态增强技术(T2*W和T1WDCE-MRI)的基本原理及其在前列腺癌的诊断和鉴别诊断、放疗方案的制定和治疗反应的评价及肿瘤复发的检出等方面的应用。
Dynamic contrast enhanced magnetic resonance imaging （DCE-MRI） enables non-invasive imaging characterization of tissue vascularity with small molecular weight gadolinium chelates. Depending on this technique, tissue blood perfusion, microvessel permeability and extraeellular leakage space can be obtained. The basic principles of two dynamic MRI techniques （T2^＊ W and T1W DCE MRI） and their applications in prostate cancer of DCE-MRI including diagnosis, differential diagnosis, formulation of treatment plan, evaluation of therapeutic reaction, detection of lesion recurrent were reviewed in this article.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第2期378-380,共3页
Chinese Journal of Medical Imaging Technology
关键词
前列腺肿瘤
磁共振成像
血管生成
Prostatic neoplasms
Magnetic resonance imaging
Angiogenesis
