摘要
目的探讨肾透明细胞癌胰腺转移瘤的临床特点。方法分析复旦大学附属中山医院自2003-01-01至2009-05-31病理确诊肾透明细胞癌胰腺转移3例病人的临床资料。结果(1)肾透明细胞癌胰腺转移瘤的B超表现为低回声团块,难以与胰腺癌鉴别;而在CT动脉期可表现为增强病灶,又难以与神经内分泌肿瘤鉴别。(2)术后病理大体标本表现为边界清晰,切面灰黄,伴有灰红色坏死区域肿块。镜下为细胞质量多呈透明色的成片状排列。(3)1例病人术后11个月死亡,另2例病人随访至2009年5月,术后生存时间分别为21个月和2个月,现仍在继续随访中。结论肾透明细胞癌胰腺转移瘤的共同特点为B超表现为低密度团块,CT表现为动脉期明显增强病灶。术前诊断主要依靠既往病史及CT检查。根治性胰腺转移瘤切除术后生存状况仍难确定,通常认为若无复发、转移,则有望获得长期生存。
Objective Analyze anti research on the clinical feathers of pancreatic metastases of renal clear cell carcinoma. Methods Collect 3 cases which were diagnosed as pancreatic metastases of renal clear cell carcinoma by pathology from January 1st, 2003 to May 31st, 2009, retrospectively analyze the clinical manifestations, physical signs, B-ultrasound and CT findings, postoperative pathology as well as the survival time after operation of pancreatic metastases of renal clear cell carcinoma. Results (1) B-uhrasound shows masses with low density, and they are difficult to distinguish from pancreatic cancer.; According to CT arterial phase, pancreatic metastases of renal clear cell carcinoma can be showed as enhanced lesions which are difficult to distinguish from neuroendocrine tumors. (2) According to the general pathology after operation, they are showed as masses with clear boundary, sallow section, accompanied with grey and red necrotic region; Cells under microscopes show numerous with transparent color (cytoplasm), and cells align like a sheet. (3) One sample patient died 11 months after the operation, and others were alive with our research until May 2009 with survival time of 21 months and 2 months respectively, and they are still alive with our research. Conclusion The follows are the common clinical Feathers of pancreatic carcinoma metastasis in renal clear cells : B-ultrasound shows masses with low density; CT arterial phase shows masses as enhanced lesions; Preoperative diagnosis basically is on the ground of medical history and CT manifestation. It' s still difficult to confirm the survival time after radical excision, People can normally survive for a long time if there' s no further metastasis happened.
出处
《中国实用外科杂志》
CSCD
北大核心
2010年第1期47-49,共3页
Chinese Journal of Practical Surgery
关键词
胰腺转移瘤
肾透明细胞癌
pancreatic metastasis
renal clear cell carcinoma