摘要
为探讨呼气末二氧化碳分压（PetCO2）与动脉二氧化碳分压（PaCO2）的相关性及其影响因素。选择成年颅内手术患者20例，全麻维持采用异丙酚60～100ug／kg.min复合异氟醚吸入，加卡肌宁6～9ug／kg.min微电脑泵输注，呼吸机控制呼吸，呼吸频率12次／分，氧流量1．5～2．0L／min。开颅后调节潮气量，使PetCO2分别为25mmHg（T1）、30mmHg（T2）、38mmHg（T3），并维持30min后采取动脉血，测定血气及生化各指标。在抽取动脉血标本时，需要保持脉搏血氧饱和度SpO2在99％～100％，各时相间心率与动脉血压之差〈±15％。得出3组间pH、PaCO2和总二氧化碳（TCO2）差异显著，而PaCO2与PetCO2之差（Pa—etCO2），HCO3^-，BE以及Na^＋、K^＋值无组间差异，这表明颅内手术控制性过度通气时，PetCO2是反映PaCO2变化的可靠指标。
To discuss the correction between PetCO2 and PaCO2 and the factors which affect them. Methods： 20 adult intracranial operation cases were selected and given general anesthesia with propofol 60- 100ug/ kg. min mixed with inhalation of isoflurane and administration of computerized pump infusion of atracurium 6-9ug/kg/min. During operation,respiration was controlled by respiratory machine, and tidal volume was 11 - 7.4mL/kg/min, respiratory rate was 12 times/min, and inhalational oxygen fluence was 1.5 - 2.0L/ min. Detection method, respiratory rate was regulated after opening skull to keep PetCO2 in the value of 25mmHg（T1 ）. 30mmHg （T2）. 38mmHg （T3） respectively for 30min, then arterial blood was sampled to check the blood gas and different biochemical indexes. And SPO2 was kept between 99% - 100%, and the difference between heart rate and blood pressure was controlled less than ± 15%. there was significant difference among pH, PaCO2 and TCO2 （P〈0. 05）, but no difference between PaCO2 and PaetCO2, HCO3^- ,and BE,Na^＋ and K^＋ （P〉0.05）. Conclusion.PetCO2 is very reliable index to show the changes of PaCO2.
出处
《石河子大学学报（自然科学版）》
CAS
2010年第1期76-78,共3页
Journal of Shihezi University(Natural Science)
关键词
开颅手术
呼气末二氧化碳分压
动脉二氧化碳分压
craniocerebral operation spartial pressure of carbon dioxide in end expiratory gas
partial pressure of carbon dioxide in arterial blood.
