摘要
目的:对QT间期离散度(△QT)与梗死相关动脉再灌注的关系进行研究,探讨是否可通过测定△QT的变化判定冠状动脉是否再通。方法:对257例急性心肌梗死(AMI)行直接PCI术后冠状动脉再通和89例溶栓治疗冠状动脉再未再通的患者进行回颐性分析,对入院时和PCI术或溶栓后第三天的12导联心电图(EKG)进行分析,△QT为最大和最小QT间期的差值。结果:再灌注组△QT明显降低,从(45.24±3.45)ms降至(37.58±4.49)ms(P<0.001),未再灌注组△QT明显增加,从(44.08±1.83)ms增加至(49.77±4.54)ms(P<0.01)。△QT增高的未再通组住院病死率高于△QT降低的再通组。结论:△QT在AMI患者冠状动脉再灌注的患者中明显降低,在冠状动脉未再通的患者中明显增加,临床可通过测定△QT的变化判定冠状动脉是否再通;△QT增高预示住院病死率增高。
Objective：To study the relationship between QT dispersion （△QT） and reperfusion of infarct-related artery,as well as how valuable △QT is as a marker for coronary reperfuson .Methods：257 patients with reperfusion after PCI and 89 patients without reperfusion who have received thrombolytic therapy in the acute phase of myocardial infarction were studied.ECG carried out on admission as well as on day 3 of patient＇s course were analyzed .△QT was defined as the difference between maximum and minimum QT interval .Results：The reperfusion group showed significant △QT reduction from （45.24±3.45）ms down to （37.58±4.49）ms （P〈0.01）.On the other hand ,the group without eperfusion showed △QT significant increase from （44.08±1.83）ms up to （49.77±4.54）ms （P〈0.01）.The in-hospital mortality of group without eperfusion was higher than that of reperfusion group .Conclusion ：The study shows that △QT is significantly reduced in patients with acute myocardial infarction submitted to PCI,and is increased in infracted patients with closed artery.△QT reduction was a predictor for coronary reperfusion of those patients,and △QT increase was a predictor for high in-hospital mortality.
出处
《中国医药导刊》
2009年第12期2020-2020,2022,共2页
Chinese Journal of Medicinal Guide
