摘要
目的评定程式化社会技能训练模式对精神分裂症患者的临床疗效。方法对204例门诊缓解期患者随机分为药物维持治疗合并程式化社会技能康复训练(观察组)和单纯药物维持治疗(对照组)进行临床对照,采用阳性与阴性症状量表(PAN-SS)、社会功能缺陷筛选表(SDSS)以及认知功能等纵向测评,随访研究24个月。结果观察组复发率(17.7%)比对照组(37.0%)低(P<0.01);两组PANSS阳性症状分(7.66±0.97vs8.34±2.04)、阴性症状分(8.13±1.15vs9.15±1.97)、总分(34.79±3.64vs37.64±5.58)及SDSS分(2.07±1.47vs2.81±1.90),观察组均明显低于对照组(P<0.01),认知功能测查改善优于对照组(P<0.05)。结论程式化社会技能训练操作性好,对降低精神分裂症患者复发,改善社会适应功能有明显临床效果。
Objective To develop psychosocial skills training module for schizophrenic outpatients.Methods Structured psychosocial skills training program,which were made according to community rehabilitation plan for schizophrenia,featured convenience and well operability.Subjects were 96 of 204 schizorenic outpatients in remission who were randomly assigned to receive psychosocial skills training combined medicine（observation group） or medicine only（control group） and followed up by 24 months.The changes during treatment were evaluated by positive and negative syndrome scale（PANSS）,Social Disability Screening Schedule（SDSS） and patients＇ cognition function were also evaluated longitudinally.Results Relapse rate of control group （37%） is higer than observation group （17.7%,P〈0.01）.After Last Observation Carried Forward（LOCF）,control group showed higer scores than observation group on positive syndrome （8.34±2.04 vs 7.66±0.97）,negative syndrome（9.15±1.97 vs 813±1.15）,total score （37.64±5.58 vs 34.79±3.64） and Social disability （2.81±1.90 vs 2.07±1.47） （P〈0.01）;observation group also showed a significant progress on cognition function（P〈0.05）.Conclusion This trial demonstrated the efficacy of the easy-operating structured psychosocial skill training grogram in preventing relapse and improving social adoptive function for schizophrenia.
出处
《中国康复理论与实践》
CSCD
2009年第12期1164-1166,共3页
Chinese Journal of Rehabilitation Theory and Practice
基金
重庆市卫生局医学科研项目计划(07-2-229)
