摘要
目的探讨支气管舒张试验对肺通气功能正常、有哮喘相关症状的疑似哮喘患者应用的意义。方法回顾性分析201例疑似哮喘患者支气管舒张试验的数据。结果201例患者中有28例舒张试验阳性;173例阴性。阴性组中有27例舒张后FEV1改善率为8%～11.9%且增加绝对值>200ml;伴有小气道功能异常患者的舒张阳性率明显增高(P<0.05);舒张前FEV1%是影响FEV1改善率及增加绝对值变化的因素(P<0.05),并且与FEV1改善率和增加绝对值均呈负相关(P<0.05)。结论支气管舒张试验可以应用于肺通气功能正常的疑似哮喘患者,尤其是舒张试验前FEV1%处于正常值低限且伴有小气道功能异常者。
Objective To analyze the significance of bronchodilator reversibility testing in suspicious asthmatic patients with normal pulmonary ventilation function.Methods The data of 201 suspicious asthmatic patients with normal pulmonary ventilation function examined by spirometry and bronchodilator reversibility testing were retrospectively analyzed.Results In all the 201 patients examined by bronchodilator reversibility testing,28 patients showed positive results and 173 patients showed negative results.There were 27 patients with improvement rate from 8% to 11.9%,but an absolute change of FEV1 measurement beyond 200ml in negative group.Positive rate of bronchodilator reversibility testing in patients with abnormal small airway function was higher than that in patients with normal small airway function （P0.05）.Pre-bronchodilator FEV1 measurement was a factor affecting improvement rate and absolute change of FEV1 measurement（P0.05）,and pre-bronchodilator FEV1 measurement was negatively correlated with improvement rate and absolute change of FEV1 measurement（P0.05）.Conclusion Bronchodilator reversibility testing play an important role in judging the state of suspicious asthmatic patients with normal pulmonary ventilation function,especially for patients with lower limit of normal of pre-bronchodilator FEV1 measurement and abnormal small airway function.
出处
《安徽医学》
2009年第11期1304-1306,共3页
Anhui Medical Journal
关键词
哮喘
支气管舒张试验
肺功能
Asthma
Bronchodilator reversibility testing
Pulmonary function
