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肝细胞癌实验诊断的研究进展 被引量:1

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摘要 在全世界,肝细胞癌(HCC)是第五位最普通的癌,在癌死亡率中是第三位最重要的原因,5年生存率仅仅7%。HCC是在慢性肝病(如肝硬化)的基础上发展的,它是一种预后很差的疾病。因此,密切追踪肝硬化病人是重要的,以便在早期阶段检出HCC,进行最佳治疗。当前用以诊断和过筛HCC的常规方法包括物理检查,超声影像学检查及血清甲胎蛋白(AFP)浓度测定。最近20年来,AFP的有关参数(如AFP mRNA和AFP的糖化型)得到广泛地研究,用作可能的新标志物诊断和监测HCC。本文简要介绍AFP及它的有关参数在诊断和监测HCC时的现代认识。
出处 《中国医师杂志》 CAS 2009年第10期1437-1439,共3页 Journal of Chinese Physician
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