摘要
斑马鱼已经成为当今人类遗传学和血液学研究的重要模式生物之一。文章介绍了斑马鱼造血系统的基本生物学特征,并重点阐述了斑马鱼在血液肿瘤学领域的应用和研究概况,显示了斑马鱼在血液肿瘤学的基础和临床研究方面均有着独特的应用前景,文章对此进行了展望。
Zebrafish is becoming a powerful vertebrate model for studies of human genetics and hematology. The biological characteristics of zebrafish organism, as well as its potential model for human blood developmental biology and hematologic malignancies are discussed. At last, we discussed the prospects of zebrafish in the clinical and basic research of hematological neoplasms.
出处
《遗传》
CAS
CSCD
北大核心
2009年第9期889-895,共7页
Hereditas（Beijing)
基金
国家自然科学基金项目(编号:30670881)
上海市科委基金项目(编号:08JC1414900)资助
关键词
斑马鱼
血液肿瘤学
动物模型
zebrafish
hematologic neoplasms
animal models
