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测定mRNA含量推断死亡时间 被引量:3

Relationship between the mRNA degradation and postmortem interval
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摘要 目前推断死亡时间的方法有很多,随着分子生物学的发展和检测技术的更新,通过测定组织细胞mRNA的含量的变化规律来推断死亡时间逐渐引起人们的注意。本文就组织mRNA的含量的测定方法,变化规律及存在的问题加以论述。 Numerous methods have been used to determine the Postmortem Interval(PMI) at present.It,however,is often very difficult to accurately determine the PMI in daily practice.With the development of molecular biology and the improvement of detection technology,quantification of mRNA degradation has recently been used to estimate the PMI.In this review article,the authors will discuss the way of quantification,the rule of degradation,as well as existing problems.
出处 《中国法医学杂志》 CSCD 北大核心 2009年第5期312-315,共4页 Chinese Journal of Forensic Medicine
关键词 法医病理学 死亡时间 MRNA降解 RT-PCR forensic pathology PMI mRNA degradation RT-PCR
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参考文献22

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共引文献109

同被引文献56

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