摘要
目的：探索丙型肝炎病毒在口腔扁平苔藓发病中的意义。方法：应用ＰＣＲ技术对６０例口腔扁平苔藓患者进行了丙型肝炎病毒ＲＮＡ的检测。结果：在６０例口腔扁平苔藓患者中，其中７例丙型肝炎病毒ＲＮＡ阳性，与对照组相比具有显著性差异（Ｐ＜０．０５）；且丙型肝炎病毒ＲＮＡ阳性患者的损害均表现为白纹伴糜烂。结论：在口腔扁平苔藓中，尤其是在糜烂伴白纹的口腔扁平苔鲜患者中，应用敏感的ＰＣＲ技术检测血液中的丙型肝炎病毒ＲＮＡ，不仅对于防治慢性肝炎，而且对于探索口腔扁平苔藓的病因与治疗均具有重要意义。
Objective:To quest the significance of hepatitis C virus in oral lichen planus(OLP) pathogenesis.Methods:PCR was applied to detect hepatitis C virus (HCV) RNA in 60 OLP cases and in 60 of healthy control.Results:The results showed that seven of OLP cases and 1 of the healthy control ( P <0.05) had positive HCV RNA. The seven cases manifested clinically erosive lesions with white stria.Conclusion:Detecting HCV RNA for OLP cases,especially erosive OLP with white stria,has an important significance not only for prevention and treatment of chronic hepatitis but also for the investigation of the causes of OLP.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
1998年第4期253-255,共3页
Journal of Practical Stomatology
