摘要
目的比较反相高效液相色谱法(RP-HPLC)法与荧光偏振免疫(FPIA)法检测肾移植患者环孢素血药浓度结果,评价二者的相关性。方法分别采用RP-HPLC和FPIA方法测定20份血样,并对结果进行统计学处理。结果两种测定方法所得结果差异无统计学意义(P>0.05)。结论RP-HPLC和FPIA方法应用于肾移植患者环孢素血药浓度监测真实可信。
Objective To compare the effects of FPIA and RP-HPLC methods in the determination of CsA. blood concentration in renal transplantation patients, and to evaluate the correlation of them. Methods 20 different concentrations of clinical samples were determined by RP-HPLC and FPIA respectively. Results There was no difference in determination results of CsA between FPIA and RP-HPLC. Conclusion FPIA and RP-HPLC methods applied on the CsA blood concentration of patients undergoing renal transplantation are true and believable.
出处
《实用药物与临床》
CAS
2009年第5期336-338,共3页
Practical Pharmacy and Clinical Remedies
