摘要
目的对比观察辅舒良与氯雷他定治疗变应性鼻炎的临床疗效。方法2008年1月—2009年1月,138例变应性鼻炎患者随机分为观察组和对照组,每组各69例,观察组采用辅舒良治疗,对照组采用氯雷他定治疗,对比观察两组的临床疗效。结果观察组与对照组治疗后1d、28d症状和体征评分均低于治疗前水平,差异有统计学意义(P<0.05);治疗后28d症状和体征评分低于治疗后1d水平,差异有统计学意义(P<0.05)。两组治疗后1d及治疗后28d症状和体征评分比较,差异无统计学意义(P>0.05)。观察组与对照组治疗的总有效率比较,差异无统计学意义(P>0.05)。两组均无严重不良反应。结论辅舒良与氯雷他定治疗变应性鼻炎均有良好疗效,均可单独用于治疗变应性鼻炎,改善患者生活质量。
OBJECTIVE To contrast and observe the clinical efficacy of fluticasone and loratadine in treatment of allergic rhinitis. METHOD From January 2008 to January 2009, 138 cases of patients with allergic rhinitis were classified into two groups, which observation group with 69 cases were treated with fluticasone and control group with 69 cases were treated with loratadine. The clincical efficacy was observed. RESULTS Compared with pre-treatment, after treatment 1d and 28 d, the score of sings and symptoms in twogroups were significantly decreased（P〈0.05 ）. Moreover, the score of sings and symptoms after treatment 25d was significantly lower than that after treatment ld. But there were no significant differences between the two groups （P〉0.05） , There was no significant difference in clinical effect between the two groups（P〉0.05）. No severe adverse drug reaction was found in either group. CONCLUSION Both fluticasone and loratadine have good therapeutic effects on allergic rhinitis. Either one can be used for allergic rhinitis alone and achieve ideal therapeutic efficacies.
出处
《中国初级卫生保健》
2009年第9期77-78,共2页
Chinese Primary Health Care
