摘要
目的比较辅舒良鼻喷剂和氯雷他定治疗变应性鼻炎的临床疗效。方法 125例变应性鼻炎患者随机分为对照组(65例)和观察组(60例)。对照组采用氯雷他定治疗,观察组采用辅舒良鼻喷剂治疗,治疗结束后比较两组的临床疗效、临床症状和体征评分。结果两组患者治疗后临床症状和体征评分均明显低于治疗前水平(P<0.05)。两组患者治疗后临床症状、体征评分及治疗总有效率相比较无明显差异性(P>0.05)。两组治疗过程中均未出现严重不良反应。结论辅舒良鼻喷剂与氯雷他定治疗变应性鼻炎均有良好疗效,均可单独用于治疗变应性鼻炎,有助于改善患者生活质量。
Objective To contrast the clinical efficacy of fluticasone and loratadine in treatment of allergic rhinitis.Methods 125 cases of patients with allergic rhinitis were randomly divided into control group(n=39) and observation group(n=43).The patients in the control group were treated by loratadine,while those in the observation group were treated by fluticasone.The clincical efficacy,scores of clinical symptoms and signs in two groups were contrasted.Results The clinical symptoms and signs scores in two groups after treatment were significantly lower than that before treatment(P0.05).There was no significant difference about clinical symptoms,signs and the total effective rate between two groups(P0.05).There were no severe adverse reactions in two groups during the treatment.Conclusion Both fluticasone and loratadine have good therapeutic effects on allergic rhinitis.Either one can be used for allergic rhinitis alone and achieve ideal therapeutic efficacies.
出处
《西部医学》
2011年第10期1949-1950,共2页
Medical Journal of West China