摘要
骨骼肌卫星细胞是位于肌细胞膜和基膜之间的具有增殖和分化潜力的生肌干细胞,对于出生后骨骼肌的生长、再生修复和维持具有重要的意义。主要对卫星细胞的含量与分布、细胞标志、可塑性和不均一性等生物学特性做了综述,最后展望了卫星细胞移植在临床上的应用前景。
Satellite cells are myogenic stem cells which lie in the plasmalemal of the muscle fiber. The basement membrane surrounding the fiber are responsible for the post-natal growth repair and maintenance of skeletal muscle. In this article, current knowledge of the cellular and molecular biology of satellite cells, such as Content and distribution, molecular makers,plasticity, nohomogeneity were mainly reviewed. Finally,the perspectire of therapy of satellite cell transplantation was in prospect.
出处
《生物技术通报》
CAS
CSCD
北大核心
2009年第10期45-48,59,共5页
Biotechnology Bulletin
基金
"863"高新技术发展计划(2006AA10Z198)
国家自然科科学基金项目(30671539)
关键词
骨骼肌卫星细胞
生物学特性
临床应用
Satellite cells Biological characteristics Clinical application
