阿奇霉素三日疗法治疗急性鼻-鼻窦炎临床观察被引量：2

Randomized Study on 3-day Regimens of Azithromycin in Treatment of Acute Bacterial Rhinosinusitis

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摘要目的观察阿奇霉素(AZM)三日疗法治疗急性鼻-鼻窦炎(ABRS)的临床疗效。方法65例ABRS患者随机分为两组,治疗组给予AZM 500 mg,每日1次口服,疗程3 d,10 g/L呋喃西林麻黄素液滴鼻,每日3次,每次每侧3滴,疗程3 d;对照组给予阿莫西林-克拉维酸片(AMC)625 mg,每日3次口服,疗程10 d,10 g/L呋喃西林麻黄素液滴鼻,每日3次,每侧每次3滴,疗程3 d。结果治疗后第7天观察组总有效率90.9%,对照组总有效率77.4%,两组比较差异有统计学意义(P<0.05);第14天治疗组总有效率96.9%,对照组87.1%,差异无统计学意义。两组临床表现分级评分均明显下降,但治疗组对减少脓涕和改善鼻塞方面优于对照组。结论AZM三日疗法治疗ABRS有良好的疗效,治疗费用较低。

作者孙文青刘运春王云霞

机构地区河南科技大学第二附属医院

出处《河南科技大学学报（医学版）》 2009年第3期224-225,共2页 Journal of Henan University of Science & Technology:Medical Science

关键词急性鼻-鼻窦炎阿奇霉素三日疗法

分类号 R765.21 [医药卫生—耳鼻咽喉科] R765.41 [医药卫生—临床医学]

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