摘要
目的探讨铁椆根调节高糖高脂大鼠肝功能的作用.方法将大鼠随机分为A、B、C、D、E、F组各8只.A组仅饲喂基础饲料,连续6周;其余5组则饲喂高糖高脂饲料3周建立高糖高脂大鼠模型,其后B组采血检验,C组继续饲喂高糖高脂饲料3周,D、E、F组则分别饲喂含铁椆根水煮液437、583、875g/kg的高糖高脂饲料3周.6周后以摘眼球取血法采血检测各组肝功能各项指标.结果高糖高脂模型大鼠肝功能主要指标与A组比较均有显著差异;饲喂铁椆根3周后,D、E、F组肝功能明显改善,与C组有显著差异(P<0.01).结论铁椆根能有效减轻肝损伤,改善肝功能.
[Objective] To investigate the effect of Cyclobalanopsis glauca root Oll liver function in high serum glucose and serum lipid model rats. [Methods] Rats were randomly divided into six groups： control goup; high serum glucose and serum lipid model group; high serum glucose and serum lipid model control group; three treated groups by Cyclobalanopsis glauca root powder with small dosage, medimn dosage, large dosage. Rats in control group were only fed with basic feeds; rats in high serum glucose and serum lipid model group and the high serun~ glucose and serum lipid model control group were fed with high-sugar and high-lipid feeds, and rats in treated groups were fed with high- sugar and high-lipid feed in supplement with different doses of Cyclobalanopsis glauca root powder. After 3-week treatment, liver fimction indexes, such as ALT, ALB and ALB/ GLB were determined. [Results] Compared with control group, the mare indexes of liver function including ALT, ALB and ALB/GLB in the high serum glucose and serum lipid modal group had significant differences〈0.01）. After3-week treated with different doses of Cyclobalanopsis glauca root powder, the liver function of high serunl glucose and serum lipid model rats was improved obviously. The ALT activity significantly declined; however, ALB and ALB/GLB increased significantly （P〈0.01）. [Conclusion] Cyclobalanopsis glauca root can relieve liver injury and improve liver function obviously
出处
《玉林师范学院学报》
2009年第3期63-65,共3页
Journal of Yulin Normal University
基金
广西自然科学基金(0728250)
玉林师范学院重点科研课题(2008YJZD11)
关键词
铁椆根
大鼠
高糖高脂
肝功能
Cyclobalanopsis glauca root
rats
high serum glucose and serum lipid
hepatic fhnction
