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焦虑症患者睡眠脑电图与认知功能的相关性研究

The variations of polysomnography and relationship between polysomnography and cognition in patients with anxiety
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摘要 目的:研究焦虑症患者睡眠脑电图和对照组之间的差异及睡眠脑电图与认知功能的相关性。方法:对符合中国精神疾病诊断与分类方案第三版(CCMD-3)焦虑性神经症20例进行多导睡眠脑电图、P300测定,对多导睡眠脑电图各参数采用t检验、方差分析并与对照组进行比较,将睡眠脑电图各参数与P300进行相关分析。结果:与正常对照组相比,焦虑症组在多导睡眠脑电图的许多指标上存在显著差异,表现醒起时间长、醒觉时间长、运动觉醒时间长、觉睡比(%)高、睡眠效率(%)低、睡眠维持率(%)低、快速眼动睡眠(REM)睡眠时间少、睡眠结构的第一阶段时间明显延长。结论:焦虑症患者睡眠脑电图改变与认知功能指标有一定的相关性。 Objective: The present study is to investigate the variations of polysomnography and relatlonship between polysomnograpny ano cognition in patients with anxiety so that we can search the better test measure of cognition and the reason of cognitive deficit .Methods: The patients twenty with anxiety was involved. The polysomnography, event- related potentials P300 were measured.Results: There are more prolonged early morning awakening and awake time,increased motion awakening time and awake/sleep, reduced sleep efficiency and maintenance, shorted Rapid Eye Movement(REM) sleep time and increased percentage of stage 1 sleep in patients with anxiety when compared with controls.Conclusion: Polysomnography in the patients with anxiety is related to event - rehed potentials P300 and Cognition.
作者 武欣 欧红霞
机构地区 南京脑科医院
出处 《中国民康医学》 2009年第18期2206-2207,2219,共3页 Medical Journal of Chinese People’s Health
关键词 焦虑症 认知功能 睡眠多导图 相关性 Anxiety Polysomnography Cognition Relationship
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