1LOK AS, HEATHCOTE EJ, HOOFNAGLE JH. Management of hepatitis B: 2000-summary of a workshop [J]. Gastroen- terology, 2001,120(7) : 1828-1853. 被引量:1
2MCMAHON BJ,ALWARD WL,HALL DB,et al. Acute hepatitis B virus infection:relation of age to the clinical expression of disease and subsequent development of the carrier state[J]. J Infect Dis, 1985,151 (4) : 599-603. 被引量:1
3VILLENEUVE JP. The natural history of chronic hepatitis B virus infection[J]. J Clin Virol,2005,34(Suppl 1):S139- S142. 被引量:1
4JAMIESON BD,AHMAD R. T-cell tolerance:exposure to virus in utero does not cause a permanent deletion of specific T cells [J]. Proc Natl Acad Sci USA,1998,85(7): 2265-2268. 被引量:1
5BERTOLEITI A,COSTANZO A,CHISARI FV,et al. Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope [J]. J Exp Med, 1994,180(3 ) : 933-943. 被引量:1
6MAINI M,BONI C,LEE CK,et al. The role of virus-specific CD8 (+) cells in liver damage and viral control during persistent hepatitis B virus infection [J]. J Exp Med,2000, 191(8): 1269-1280. 被引量:1
7SHIMIZU Y,GUIDOTTI LG,FOWLER P,et al. Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice[J]. J Immunol, 1998,161 (9) : 4520--4529. 被引量:1
8THIMME R,WIELAND S,STEIGER C,et al. CDS(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection[J]. J Virol,2003,77(1):68- 76. 被引量:1
9OKAZAKI T,WANG J. PD-1/PD-L pathway and autoimmunity[J]. Autoimmunity,2005,38(5) : 353-357. 被引量:1
10GREENWALD ILl,FREEMAN GJ,SHARPE AH. The B7 family revisited[J]. Annu Rev Immunol, 2005,23 : 515-548. 被引量:1
5MCMAHON BJ,ALWARD WL,HALL DB,et al.Acute hatitis B virus infection:relation of age to the clinical ex-pression of disease and subsequent development of the carrierstate[J].J Infect Dis.1985,151(4):599-603. 被引量:1