摘要
目的:研究沙生蜡菊花的化学成分。方法:采用多种色谱方法(硅硅硅色谱硅ODS硅色谱和HPLC硅色谱)分离纯化,依据理化性质、核磁数据分析并结合CD谱进行结构鉴定。结果:从沙生蜡菊花的甲醇提取物中分离得到8个二氢黄酮类化合物,分别鉴定为(2S)-Helichrysin A(1)、(2R)-Helichrysin A(2)、Naringenin-7-O-β-D-glucopyranoside(3)、(2R,3R)-Dihydrokaempferol-7-O-β-D-glucoside(4)、Helicioside A(5)、(2R)-Eriodictyol-5-O-β-D-glucoside(6)、(2S)-Naringenin-5,7-di-O-β-D-glucoside(7)、(2R)-Naringenin-5,7-di-O-β-D-glucoside(8)。结论:化合物4～8为从该属植物中首次分离得到的化合物,化合物2、3为从该植物中首次分离得到的化合物。
AIM： To study the chemical constituents of Helichrysiflos syn. METHOD： The chemical constituents were isolated by various methods of isolation （silica gel, ODS and HPLC column chromatography） and their structures were elucidated by the analysis of spectral data, CD spectral data and chemical properties. RESULT： Eight flavonones compounds were isolated from the MeOH extract of Helichrysi flos syn. The chemical structures were elucidated as （2S）-Helichrysin A （1）, （2R）-Helichrysin A （2）, （2S）-Naringenin-7-O-β-D-glucopyranoside （3）, （2R,3R）-Dihydrokaempferol 7-O-β-D-glucoside （4）, Helicioside A （5）, （2R）-Eriodictyol-5-O-β-D-glucoside （6）, （2S）-Naringenin-5,7-di-O-β-D-glucoside （7）, （2R）-Naringenin-5,7-di-O-β-D-glucoside （8）. CONCLUSION： Compound 4-8 were obtained from Helichrysum Mill. for the first time, compound 2, 3 were obtained from Helichrysum arenarium （L.） MOENCH for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2009年第5期357-360,共4页
关键词
沙生蜡菊花
化学成分
结构鉴定
Helichrysiflos syn.
Chemical constituents
Structural determination
