摘要
目的:探讨1例原发性骨淋巴瘤(PLB)的诊断、治疗及患者预后。方法:报告1例PLB患者,并结合国内外相关文献进行分析。结果:该例患者依据病变局灶活检及免疫组化结果被确诊为"弥漫大B细胞型非霍奇金淋巴瘤"。予患者常规化疗,结合单克隆抗体治疗及自体造血干细胞移植后,14个月后达到完全缓解,随访36个月,未出现新发病灶。结论:PLB的实验室检查结果和影像学表现均无特异性,早期确诊十分困难,易误诊。目前,确诊PLB依靠病理组织形态学和免疫组化检查。早期诊断、积极治疗可改善PLB患者的预后。
Objective To study the diagnosis, treatment and prognosis of a patient with primary lymphoma of bone （PLB）. Methods A case of primary lymphoma of bone was reported and the pertinent literature was reviewed. Results The patient was diagnosed as non-Hodgkin＇s lymphoma in the early stage via biopsy of local lesion, and complete remission was achieved by routine chemotherapy in combination with treatment of monoelone antibody and autologous hematopoietic stem cell transplantation. No novel lesion was found during the 36 months of follow up. Conclusions The diagnosis of PLB should be established by histopathologieal and immunohistochemistry examinations. Early diagnosis and active therapy could improve the prognosis of PLB.
出处
《诊断学理论与实践》
2009年第4期410-414,共5页
Journal of Diagnostics Concepts & Practice
关键词
原发性骨淋巴瘤
诊断
病理
Primary lymphoma of bone
Diagnosis
Pathology
