摘要
目的:评价西酞普兰治疗抑郁症的疗效及安全性。方法:将62例抑郁症患者随机分成两组,西酞普兰组和阿米替林组各31例,对两组均进行6周的治疗观察。用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)进行评定。结果:两组HAMD减分率比较差异无显著性(P>0.05);不良反应方面,阿米替林组不良反应广泛且较西酞普兰组严重。结论:西酞普兰是一种有效的、安全性优于阿米替林的抗抑郁药。
Objective：To compare the clinic effects and the safety of Citalopram and Amitriptyline in treatment of depression. Methods ：62patients with depression were randomly divided into two groups; 31 patients took Citalopram and others took Amitriptyline. All patients were treated for 6 weeks; HAMD and TESS were evaluated before treatment and at the end of the frist,2th ,4th ,6thweeks after the treatment. Results： The effect of Citalopram and Amitriptyline had no significant difference（ P 〉 0.05 ）, The safety of Citaloprama were hither than Amitriptyline. Conclusions： The patients with Citaloprama treated have better curative effect and fewer side effects than Amitriptyline.
出处
《中国民康医学》
2009年第17期2066-2067,共2页
Medical Journal of Chinese People’s Health
