摘要
磷酸钙骨水泥(CPC)作为骨修复材料近年来已在临床广泛应用,但因材料特性使其在应用时存在某些缺陷,需要加以改进。在本文中,我们综合评述了目前对CPC在调整固化时间,增加机械强度,提高生物降解性三方面所作出的理化性能改进的研究,并且阐述了以CPC为载体与药物、生长因子等构建复合物,以更好修复骨缺损的实验研究进展。
In recent years, Calcium Phosphate Cement （CPC） as a bone repair material has been widely applied in the clinical treatment. However due to its special properties, there are some deficiencies in its applications, which need to be improved. In this paper, we reviewed the research on the physicochemical properties of CPC in three areas, adjusting its＂ solidifying time, increasing its mechanical strength and enhancing its biodegradability. And it also set out the progress of experimental study on the applications of CPC as the carrier of drugs, growth factors etc. to build composites, that can repair the bone defects better.
出处
《材料科学与工程学报》
CAS
CSCD
北大核心
2009年第4期649-652,共4页
Journal of Materials Science and Engineering
基金
浙江省科技厅资助项目(2007C23SA800002)
浙江省中医药管理局资助项目(2009CBD38)
关键词
磷酸钙骨水泥
理化性能
骨修复
calcium phosphate cement
physicochemical properties
bone repair
