摘要
合成了α—氨基保护的Ｌ—Ａｓｐ和α—羧基保护的Ｌ—ｐｈｅ，分别得到了Ｚ—Ｌ—Ａｓｐ（苄氧羰酰—Ｌ—天冬氨酸）和Ｌ—ｐｈｅ—ＯＭｅ·ＨＣｌ（Ｌ—苯丙氨酸甲酯盐酸盐），产率分别达７５．７％和９２．３５％。经熔点、旋光值测定和薄层层析，表明两种产物纯度极高。
Two substrates of synthesizing aspartame—a new type of sweater, L—Asp of α—NH2 protected with carbo—benzoxy group, Z—L—Asp, and L—phe of α—COOH protected with methyl ester, L—phe—OMe·HCl,were symthesized. The yields of Z—L—Asp and L—phe—OMe·HCl were 757% and 9223% respectively. Analyzing with melting points and optical activities determined, and with TLC, these two products were qualified.
出处
《延安大学学报（自然科学版）》
1998年第2期40-43,共4页
Journal of Yan'an University：Natural Science Edition
