摘要
连翘苷是肺毒清颗粒中重要的有效成分,是质量控制的监测指标,本论文优化了肺毒清颗粒中连翘苷的水提取工艺并建立了测定连翘苷含量的HPLC方法。通过L9(34)正交试验优化水提取工艺,确定了肺毒清原药材的最佳水提工艺为用10倍量水煎煮3次,每次1h。采用正交设计优化的工艺提取肺毒清颗粒中的连翘苷,提取率高,工艺稳定可行。
To optimize the process of extracting phillyroside and extract content from Feiduqing granules. The effect of solvent fold, extract times was investigated with the three factor at three level orthogonal test. Results： The analysis result indicated the optimum conditions of was 10 fold solvent and 3 times for extraction each 1 h. It was showed that the optimum model was highly predictive,the process is stable.
出处
《药物生物技术》
CAS
CSCD
2009年第4期377-379,共3页
Pharmaceutical Biotechnology
