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从改善“种子”细胞入手提高干细胞移植效率 被引量:1

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摘要 尽管随着人们健康意识的提高,通过控制危险因素、最佳药物治疗和再血管化治疗,缺血性心脏病的发病率和死亡率明显下降。然而据统计,每年全球仍有大约两千万患者死于缺血性心脏病。已有基础研究结果显示,干细胞移植通过再血管化、新生心肌等途径可以改善缺血心肌局部灌注,增加存活心肌数量,有助于改善心脏功能。从2002年到2008年,超过2000例患者入选干细胞移植临床研究,大多数前瞻性随机对照研究、队列研究以及病例报告均认为干细胞移植安全,并且有助于改善急性心肌梗死、陈旧性心肌梗死及心肌梗死后心力衰竭的临床症状与心脏功能,极有可能成为冠心病治疗的辅助手段之一。
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2009年第8期675-679,共5页 Chinese Journal of Cardiology
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