摘要
设计合成一个柔性插入配体dcpip(dcpip=2–(2,3–环己烯基咪唑并[4,5-f]邻菲咯啉)及其钌(II)多吡啶配合物[Ru(bpy)2(dcpip)](ClO4)2(bpy=2,2'–联吡啶)和[Ru(phen)2(dcpip)](ClO4)2(phen=1,10–邻菲咯啉)。采用元素分析和质谱对其进行表征。用电子吸收光谱、荧光光谱和粘度测试研究配合物与DNA作用。研究结果表明,配合物与DNA之间通过插入作用结合。
A new ligand dcpip and its mthenium（Ⅱ） complexes [Ru（bpy）2 （dcpip）]2＋ （bpy = 2,2＇-bipyridine） and [Ru（phen）2（dcpip）]^2＋ （phen = 1,10- phenanthroline, dcpip 2-（2,3-cyclohexeny｜）imidazo[4,5-f][1,10]phenanthroline） were synthesized and characterized by elemental analysis and mass spectra. The DNA-binding properties of these complexes were investigated by spectroscopic methods and viscosity measurement. The experimental results indicated that the two complexes interact with calf thymus DNA （CT-DNA） by intercalative mode.
出处
《广东化工》
CAS
2009年第7期34-36,共3页
Guangdong Chemical Industry
关键词
钌(Ⅱ)配合物
光谱
DNA结合
ruthenium（Ⅱ） complexes
spectroscopy
DNAcombination
