摘要
目的通过对临床发生的药品不良反应（adverse drug reacition，ADR）的分析，为临床合理用药提供信息，减少不良反应的发生。方法分析我院2007年4月至2008年12月，全院临床科室ADR报告中涉及的患者年龄、药品种类、给药途径、临床表现和转归情况进行统计分析。结果女性ADR的发生率高于男性，ADR累及的系统器官主要为皮肤、神经系统、呼吸系统、消化系统。临床表现皮疹，局部红肿、红斑、搔痒、头晕、头痛、发热、出汗、寒颤、胸闷、气促心慌、呼吸困难、恶心、呕吐、腹胀、腹痛等。结论合理理使用抗菌素：使用中药针剂时需辩证用药，且尽量避免与其他药物配伍，严格控制剂量和滴速，减少和避免ADR发生。
Objective According to the analyses of adverse drug reactions （ADR） in clinic, we supply reasonable drug information for clinical usage to reduce recurrence of adverse reactions. Methods Analyze the ADR reports of our hospital from April, 2007 to December, 2008 and make statistical analysis by terms of age of patients, kinds of drugs, route of administration, clinical manifestation, and recovery, etc. Result The incidence rate of ADR in the female is more than the male. ADR mainly involves with the skin, nervous system, respiratory system, and digestive system. Clinical manifestations mainly show as rash, local swelling, erythema, irritations, dizziness, headache, fever, sweating, shiver, chest tightness, short breath, heart palpitation, dyspnea, sickness, vomiting, abdominal pain and distension etc. Conclusion Antibiotics should be reasonably used; Traditional Chinese medicinal injection should be used according to syndrome differentiation and be avoided used with the combination with other medicines. Dosage and injecting speed should also be strictly controlled to reduce and avoid ADR happening again.
出处
《国际中医中药杂志》
2009年第4期367-368,共2页
International Journal of Traditional Chinese Medicine
关键词
药品不良反应
抗菌素
中药注射剂
Drug adverse reaction
Antibiotic
Injection of traditional Chinese medicine
