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剪切力诱导细胞骨架重组在力学信号转导机制中的作用 被引量:2

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摘要 细胞能感知和传递剪切力并引起相应的反应以适应新的力学环境,从而保持内环境的稳定,这种适应既有结构性的变化,也有代谢性的变化。许多研究显示剪切力诱导的细胞骨架变化在力学信号转导中发挥着重要作用,并通过多种力学感受器感知和调节复杂的信号转导通路。剪切力引起细胞形态和结构的变化,其中细胞骨架重组及其基因表达的变化在这一过程中扮演中心角色。该文侧重就剪切力作用下骨组织细胞的细胞骨架重组在力学信号转导机制中的作用作一综述。
出处 《国际骨科学杂志》 2009年第4期257-260,共4页 International Journal of Orthopaedics
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参考文献2

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共引文献6

同被引文献47

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