摘要
目的探讨血清唾液酸（Sialic Acid，SA）水平与冠状动脉粥样性心脏病（CHD）的严重程度及SA与CHD危险因素的相关性。方法利用Olympus400全自动生化分析仪分别检测对照人群及CHD患者血清中总唾液酸（1、SA）的水平。同时检测了血脂和纤维蛋白原水平。结果CHD组TSA的含量明显高于对照组（P〈0．01），急性心梗（AMI）患者SA含量〉不稳定心绞痛（UAP）〉稳定性心绞痛（SAP）。CHD纽TSA的含量与血甘油三酯及血浆纤维蛋白原水平有显著相关性。结论血清唾液酸水平的升高与GHD的发生有关，而且可以作为判断冠心病病情程度的一项临床生化指标。
Objective To investigate the correlation between serum sialic acid and the severity degree of coronary heart disease（CHD） as well as some risk factors of CHD. Methods The Olympus 5400 - type automatic biochemical analyzer was employed to detect the content of total sialic acid in patients with CHD and healthy controls. The content of blood fat and Fibrinogen were also detected. Results The content of serum TSA in CHD group was significantly higher than that in healthy control （ P 〈 0. 01 ）, the content of patients with acute myocardial infarction （AMI） 〉 unstable angina pectoris （UAP） 〉 stable angina pectoris （SAP）. There was a significant correlation between serum sialic acid and blood fat as well as Fibrinogen. Conclusion The increased serum TSA correlates with onset of CHD, and it could be used as a clinical biochemical indicator to judge the patient＇s condition.
出处
《中外医学研究》
2009年第7期19-20,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
血清唾液酸
冠心病
危险因素
Serum Sialic acid Cornary heart disease Risk factors
