摘要
目的评价邓铁涛经验方治疗急性冠脉综合征(ACS)冠脉介入后患者的疗效与安全性。方法将ACS冠脉介入后气虚痰瘀证患者62例随机分为治疗组(邓铁涛经验方及常规治疗)与对照组(常规治疗),比较两组中医证候积分、生存质量、心绞痛分级与心血管事件,并进行安全性评价。疗程14d,随访1个月。结果两组患者治疗第15天、随访第30天中医症状计分比较,差异均有统计学意义(P<0.05),治疗组低于对照组。两组患者治疗后西雅图心绞痛量表(SAQ)各维度积分比较,躯体活动受限程度、心绞痛稳定状态、治疗满意程度维度差异有统计学意义(P<0.05),治疗组优于对照组;心绞痛发作情况、疾病认识程度维度差异无统计学意义(P>0.05)。两组患者治疗第15天、随访第30天心绞痛分级比较,差异无统计学意义(P>0.05)。两组患者治疗期间、随访1个月均无心血管事件发生。结论益气除痰兼以活血功效的方药可改善ACS冠脉介入后患者的临床症状,提高生存质量。
Objective To evaluate the effect and safety of experienced prescriptions of Deng Tietao on acute coronary syndrome （ACS） patients（pts） undergoing percutaneous coronary intervention（PCI）. Methods The clinical randomized control trial was adopted. The object of the study include the ACS pts undergoing PCI who diagnosed by syndrome of Qi - deficiency and phlegm and stagnated blood. To compare symptom integral of traditional Chinese medicine（TCM） and quality of life,grade of angina pectoris and incident of cardiovascular event between the treatment group treated by experienced prescriptions of Deng Tietao plus conventional therapy and the control group treated by conventional therapy. The course of treatment was 14 days,and follow - up I month. Results The symptom integral of TCM in the treatment group was lower than that in the control group,and there was statistical significance in 15th day after treatment and 30th day after follow-up（P〈0.05）. The integral of physical limitation（PL）,angina stability（AS）and treatment satisfaction（TS）for Seattle angina questionnaire（SAQ） in the treatment group was better than that in the control group（P〈0.05）. There was no statistical significance in the integral of angina frequency（AF）and disease perception（ DP） for SAQ and the grade of angina pectoris in 15th day after treatment and 30th day after follow - up between the two groups（P〉0.05）. There was no cardiovascular event during treatment and follow - up in the two groups. Conclusion Experienced prescriptions of Deng Tietao which had effects of reinforcing Qi.expeling phlegm and activating blood could alleviate clinical symptoms and improve quality of life on ACS pts undergoing PCI.
出处
《中西医结合心脑血管病杂志》
2009年第7期757-759,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
广州中医药大学邓铁涛基金第三批立项课题(No.13)
关键词
中医
急性冠脉综合征
冠脉介入
生存质量
traditional Chinese medicine
acute coronary syndrome
percutaneous coronary intervention
quality of life
