摘要
目的:探讨乳腺癌患者腋窝淋巴结转移的相关因素。方法:回顾性分析675例乳腺癌患者的病理资料,探讨雌激素受体、孕激素受体、人表皮生长因子受体表达规律并分析其与腋窝淋巴结转移的关系。结果:腋窝淋巴结阳性率43.72%,雌激素受体、孕激素受体、Ki-67蛋白阳性率分别为67.16%,71.12%,91.75%,人表皮生长因子受体过表达率14.19%。雌激素受体、孕激素受体、Ki-67蛋白、人表皮生长因子受体与淋巴结转移无相关性。结论:淋巴结转移与雌激素受体、孕激素受体、Ki-67蛋白、人表皮生长因子受体表达是相对独立、相互补充的乳腺癌预后因素。
Objective To explore the pathological characteristic of breast cancer. Methods The expression of C erbB-2, estrogen receptor and progesterone receptor and its relationship with axillary lymph nodes metastasis was retrospectively analyzed in 675 patients with breast neoplasms. Results The positive rate of invasion of axillary lymph nodes was 43. 72%. The positive rates of estrogen receptor, progesterone receptor and Ki-67 were 67. 16%, 71. 12% and 91. 75% respectively. The overexpression rate of C-erbB-2 was 14. 19%. Estrogen receptor, progesterone receptor, C-erbB-2 and Ki-67 were not correlated to metastasis of axillary lymph nodes. Conclusion Metastasis of lymph nodes is a relatively independent prognostic factor of breast cancer from estrogen receptor, progesterone receptor, C-erbB-2 and Ki-67.
出处
《中华实用诊断与治疗杂志》
2009年第7期669-670,共2页
Journal of Chinese Practical Diagnosis and Therapy
