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调和阴阳法对中风患者血浆降钙素基因相关肽及血管内皮素水平的影响 被引量:7

Effect of Acupuncture Therapy of Regulating Yin and Yang on Plasma Levels of Calcitonin Gene-related Peptide and Vascular Endothelin in Stroke Patients
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摘要 【目的】观察调和阴阳法治疗中风病的疗效及对血浆降钙素基因相关肽(CGRP)和血管内皮素(ET)水平的影响。【方法】将120例中风病患者随机分为实验组、传统体针组、头针组各40例,分别采用调和阴阳法、传统体针法和单纯头针法针刺治疗。1个半月为1个疗程,共治疗2个疗程。观察临床疗效及治疗前后患者血浆CGRP、ET水平的变化。【结果】(1)总有效率实验组为95.0%,传统体针组为85.0%,头针组为82.5%,实验组与传统体针组、头针组比较,差异均有显著性意义(P<0.01)。(2)3组治疗后血浆CGRP含量均较治疗前显著升高(P<0.01);对3组血浆CGRP含量治疗前后差值进行两两比较,实验组与传统体针组、头针组比较,差异均有显著性意义(P<0.01),而传统体针组与头针组比较,差异无显著性意义(P>0.05)。(3)3组治疗后血浆ET含量均较治疗前显著降低(P<0.05或P<0.01);对3组血浆ET含量治疗前后差值进行两两比较,实验组与传统体针组、头针组比较,差异均有显著性意义(P<0.01),而传统体针组与头针组比较,差异无显著性意义(P>0.05)。【结论】调和阴阳法对中风患者有较好的治疗作用,并具有上调血浆CGRP含量,降低ET水平的作用。 Objective To observe the effect of acupuncture therapy of regulating Yin and Yang for the treatment of stroke, and to investigate the influence on plasma levels of ealcitonin gene-related peptide (CGRP) and vascular endothelin (ET). Methods One hundred and twenty stroke patients were equally randomized into 3 groups: group A received acupuncture therapy of regulating Yin and Yang, group B received traditional body acupuncture therapy, and group C received scalp acupuncture therapy. One and a half months constituted one treatment course, and the treatment lasted 2 courses. The therapeutic effect was evaluated and the changes of plasma CGRP and ET levels were observed. Results The total effective rate was 95.0% in group A, 85.0% in group B, and 82. 5% in group C, the difference being significant between the three groups ( P 〈 0. 01 ). Plasma CGRP level was increased ( P 〈 0. 01 ) and ET level decreased ( P 〈 0. 05 or P 〈 0. 01 ) in the 3 groups after treatment. The difference values of CGRP and ET before and after treatment in group A differed from those in groups B and C (P 〈 0. 01 ), and the difference between groups B and C was insignificant ( P 〉 0. 05 ). Conclusion Acupuncture therapy of regulating Yin and Yang exerts a certain effect for the treatment of stroke, and can up-regulate plasma CGRP level and decrease ET level.
出处 《广州中医药大学学报》 CAS 2009年第4期347-350,共4页 Journal of Guangzhou University of Traditional Chinese Medicine
基金 广东省中医药局课题(编号:2050038)
关键词 调和阴阳法 中风病/针灸疗法 血浆降钙素基因相关肽 血管内皮素 ACUPUNCTURE THERAPY OF REGULATING YIN AND YANG STROKE/acup-mox therapy CALCITONIN GENE-RELATED PEPTIDE VASCULAR ENDOTHELIN
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