摘要
目的：探讨钙维它（Ｃａｌｖｉｔａｌ）盖髓后纤维粘连蛋白（Ｆｉｂｒｏｎｅｃｔｉｎ，Ｆｎ）在牙髓中的分布和作用。方法：家犬前磨牙Ｃａｌｖｉｔａｌ盖髓术。用免疫组织化学方法观察Ｆｎ的分布和表达。结果：术后２周，Ｆｎ染色见于变性坏死层、修复性牙本质基质表面，牙髓中炎细胞、成纤维细胞、成牙本质细胞样细胞、成牙本质细胞周围。术后６周～１０周，成纤维细胞、成牙本质细胞样细胞与牙本质基质交界处，成纤维细胞细胞浆Ｆｎ阳性，成牙本质细胞样细胞Ｆｎ弱染或阴性。矿化的牙本质Ｆｎ阴性。结论：Ｃａｌｖｉｔａｌ盖髓后的牙髓修复过程中有Ｆｎ表达。
Aim: To investigate the localization of fibronectin during dental pulp repair.Methods:12 Calvital capped premolars were chosen to detect the distribution of fibronectin by SABC assay. Results: Fibronectin was detected at the surfaces or interfaces of necrotic zone, capping agent , newly deposited matrix and associated matrix forming cells. Intracellular staining was seen in macrophages at 14 days and was progressively localized in pulp fibroblasts from 6 weeks post- operatively,while odontoblast-like cells were weakly stained. Mineralized dentine showed little reaction. Conclusions: The distribution of fibronectin indicates it may contribute to dentinogenesis induced by Calvital.
出处
《牙体牙髓牙周病学杂志》
CAS
1998年第2期89-91,共3页
Chinese Journal of Conservative Dentistry
