摘要
采用ＣＤ３１免疫组化染色检测４８例乳腺浸润癌间质的微血管数及癌细胞ＣＤ４４Ｖ６，ＥＧＦＲ的表达。结果发现存在于远处淋巴结或脏器转移及ＣＤ４４Ｖ６，ＥＧＦＲ阳性表达的乳腺浸润癌的微血管数显著高于无转移者及ＣＤ４４Ｖ６，ＥＧＦＲ阴性者。提示乳腺浸润癌的血管新生。
Microvessel quantity(MVQ), expression of CD44V6 and EGFR were studied in 48 patients with invasive breast carcinoma by CD31 immunohistochemistry. Significant differences of MVQ, CD44V6 and EGFR were observed (P<0.01) between the groups with and without metastasis. The results suggest that angiogeneses and activation of tumor metastasis associated gene play an important role in tumor metastasis.
出处
《湖南医科大学学报》
CSCD
1998年第3期243-245,248,共4页
Bulletin of Hunan Medical University
关键词
微血管数
乳腺癌
肿瘤浸润
肿瘤转移
breast neoplasm
carcinoma
immunohistochemistry
microvessel quantity
diagnosis
metastatis
