摘要
目的分析本院2006年8月至2008年8月临床分离的铜绿假单胞菌分布特征及药物敏感性,为临床治疗提供参考。方法将本院患者送检各类标本进行分离、培养,用法国梅里埃VITEK-32全自动微生物测试仪进行细菌培养鉴定和药敏试验。结果分离出352株铜绿假单胞菌,主要来自痰(62.5%)和伤口分泌物(21.3%);科室分布以神经外科、重症监护病房和外科最多,分别占27.6%、22.7%和14.8%;其对氨苄西林、氨苄西林/舒巴坦、头孢曲松、头孢唑啉、呋喃妥因、复方新诺明等多种抗菌药物耐药率高,亚胺培南和哌拉西林/他唑巴坦敏感率最高,分别为79.5%和73.8%。结论铜绿假单胞菌最主要来自痰,对多种抗菌药物均产生不同程度的耐药性,临床治疗感染要以药敏试验为基础。
Objective To analyze the distribution and drug sensitivity of PA, and provide reference for the clinical treatment. Methods Separating the specimens from the patients in our hospital and conducting the experiment for drug sensitivity. Resuits The separated 352 strings of PA are mainly from sputum（62.5%）and wound exudates（21.30%） ; Department distributions are neurosurgery department （27.6%） and ICU surgical department （22. 7%）. It is of high rates of resistance for antimicrobial medicines such as Ampicillin, Ampicillin/Sulbacfam, Ceftriaxone, Cefazolin, Furadantine, Co-trimoxazole among which Imipenem and Piperacillin/Tazobactam enjoying as highest rates of resistance as 79.5% and 73.8%. Conclusion The separation of PA is mainly from sputum and shows the high rates of resistance to antibiotics; The testing for antibiotics drug allergy is essential for the clinical treatment for infection.
出处
《检验医学与临床》
CAS
2009年第13期1065-1066,共2页
Laboratory Medicine and Clinic
