摘要
软骨组织工程的出现,为解决软骨修复这个临床难题提供了新的方法。然而寻找一种合适的生物载体材料是目前软骨组织工程的热点。胶原是一种天然支架材料,具有良好的生物相容性、可降解性和生物活性,可作为细胞三维生长支架,并且有维持种子细胞增殖、黏附和分化的能力。本文就胶原及其复合材料在软骨组织工程方面的应用状况与前景作一综述。
Recently, tissue- engineered chondrocyte transplantation has been tried to treat full - thickness cartilage defects. Of the many scaffold materials being investigated, collagen, with good biocompatibility, biodegradable and biological activity, has been shown to have many advantageous features for the proliferation, the attachment and the differentiation. The pres- ent article reviews the applications and prospects of collagen in cartilage tissue engineering.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2009年第13期998-1000,共3页
Orthopedic Journal of China
关键词
胶原
软骨修复
组织工程
collagen
cartilage repair
tissue engineering