摘要
目的探讨放大内镜窄带成像下胃小凹的形态分类及其临床病理意义。方法应用放大内镜窄带成像术对164例因消化不良症状就诊患者进行检查,通过分析内镜观察到胃黏膜结构的改变,制定出A型(圆点状)、B(线状)、C型(稀疏粗大的线状)、D型(斑块状)和E型(绒毛状)5型胃小凹形态分类,并与相应328个病变组织的病理组织学改变进行比较分析。结果A、B、C、D和E共5型分别见于从正常到重度萎缩、重度肠上皮化生,并与慢性炎症及肠上皮化生的程度呈明显正相关,异型增生主要见于D型和E型胃黏膜。结论5种基本胃小凹形态与病理组织学改变存在密切关系,通过放大内镜窄带成像准确识别5种胃小凹形态将有助于对萎缩、肠上皮化生及异型增生等常见胃黏膜病变的诊断。
[Objective] To explore the classification of gastric pits under magnifying endoscopy with narrow band imaging and their clinicopathological significance. [Methods] A total of 164 patients with dyspepsia were examined by magnifying endoscopy with narrow band imaging. After analyzing the microstructure of gastric mucosa, the morphology of gastric pits was classified as follows： type A （round spot pits）, type B （linear）, type C （sparsely and thickly linear）, type D （patchy） and type E （villous）, which were compared to the histopathological findings of 328 biopsies from gastric mucosa. [Results] Types A, B, C, D and E were respectively found from normal gastric mucosa to mucosa with sever atrophy and intestinal metaplasia, and the positive correlation was found between types A, B, C, D, E and the degree of chronic gastritis or intestinal metaplasia. Dysplasia was mostly found in gastric mucosa of type D and type E. [Conclusions] Five types of gastric pits were closely related to histopathologic findings, and the identification of gastric pits though magnifying endoscopy with narrow band imaging would help in the diagnosis of the common gastric mucosal lesions including atrophy, intestinal metaplasia and dysplasia.
出处
《中国内镜杂志》
CSCD
北大核心
2009年第5期466-468,共3页
China Journal of Endoscopy
关键词
放大内镜
窄带成像
胃小凹
病理
magnifying endoscopy
narrow band imaging
gastric pit
pathology
