摘要
目的探讨菌血症患者病程中出现的肝功能异常的情况及对菌血症早期诊断的临床意义。方法选择经实验室检测确认的菌血症患者165例为菌血症组,患细菌感染的非菌血症患者138例为非菌血症组,两组均无肝脏疾病。菌血症组以第一瓶阳性血培养采集当天的肝功能结果为依据,比较两组结果间的肝功能差异。结果菌血症组的谷氨酰基转移酶(GGT),碱性磷酸酶(ALP)显著升高,白蛋白(ALB)显著降低,与非菌血症组比较有非常显著性差异(P<0.01),天冬氨酸氨基转移酶(AST),总胆红索(TB)两组无明显变化(P>0.05)。结论肝功能指标中的GGT、ALP、ALB有助于早期诊断菌血症。
Objective To investigate the changes of liver function in patients during the course of bacteremia , and explore its potential predicting value on bacteremia. Methods There were 165 patients with laboratory - confirmed bacteremia, and 138 non - bacteremia patients with bacterial infections as control group. The two groups had no underlying liver diseases. The liver function indices of two groups were compared statistically on the day while the first cuvette of blood was obtained and cultured. Results Serum levels of GGT and ALP were significandy higher, and serum ALB was significantly lower in bacteremia group than that in control group （P 〈 0.01 ）, nevertheless, serum level of AST, TB showed no significant difference between two groups（P 〉 0.05 ）. Conclusion Indices of liver function may be useful in predicting bacteremia at early stage.
出处
《湖北中医学院学报》
2009年第3期28-29,共2页
Journal of Hubei College of Traditional Chinese Medicine
关键词
菌血症
肝功能指标
诊断
Bacteremia
Liver function
Diagnosis
