摘要
目的分析医院临床培养分离出的病原菌分布及耐药情况,了解其变化趋势,为临床的预防和治疗提供可靠依据。方法对医院2005年1月1日-2007年12月31日分离出的17 923株菌株,分析其分布、抗菌药物的耐药情况及变化趋势。结果排在前9位的病原菌依次为铜绿假单胞菌、金黄色葡萄球菌、大肠埃希菌、粪肠球菌、肺炎克雷伯菌、鲍氏不动杆菌、表皮葡萄球菌、嗜麦芽寡养单胞菌及屎肠球菌;革兰阳性球菌中以金黄色葡萄球菌位居首位,耐甲氧西林金黄色葡萄球菌(MRSA)呈现下降的趋势,ESBLs+大肠埃希菌呈现逐渐升高的趋势。结论分离出的病原菌仍然是医院患者的常见感染菌,同时,产ESBLs+大肠埃希菌和肺炎克雷伯菌呈现逐渐升高的趋势,且对多种抗菌药物耐药,临床上要引起高度的重视。
OBJECTIVE To investigate the distribution and resistance the bacteria isolated from the patients of our hospital, to provide reliable laboratory evidences for the clinical precaution and therapy. METHODS The antibiotic susceptibility of 17 923 bacteria strains isolated from the inpatients between 1 Jan 2005 and 31 Dec 2007 of our hospital was detected. RESULTS The top nine bacteria were Pseudomonas aeruginosa, Staphyloccocus aureus, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Acinetobacter baurnannii, Staphylococcus epidermidis, Stenotrophomonas maltophilia and Enterococcus faecium. S. aureus was the top one in Gram-positive bacteria （G^＋ bacteria）. The occurrence of meticillin-resistant S. aureus（MRSA） statistically decreased. The occurrence of ESBLs^＋ E. coli statistically increased. CONCLUSIONS These bacteria are still the common detected types in the patients of our hospital. It should be noted that K. pneumoniae and ESBLs^＋ E. coli strains are increasing gradually and they are resistant to varieties of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第11期1413-1415,共3页
Chinese Journal of Nosocomiology
关键词
病原菌
分布
耐药性
趋势
Bacteria
Distribution
Resistance
Tendency
