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胃癌患者CEA、CA19-9与CA72-4联合检测的临床意义 被引量:8

胃癌患者CEA、CA19-9与CA72-4联合检测的临床意义
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摘要 目的探讨血清CEA、CA19-9、CA72-4单项检测与联合检测在胃癌诊断中的价值。方法采用电化学发光技术检测63例胃癌患者、71例良性胃病血清CEA、CA19-9、CA72-4的含量。结果胃癌患者血清CEA、CA19-9、CA72-4的阳性检测率明显高于良性胃病对照组,差异有显著性(P<0.01)。三者联合检测灵敏度显著提高(P<0.05)。结论血清CEA、CA19-9、CA72-4联合检测有助于提高胃癌诊断的灵敏度。 Objective To study the value of combined detection of serum CEA, CA19-9 and CA72-4 in diagnosis of patients with gastric cancer. Methods Serum levels of CEA, CA19-9 and CA72-4 were measured by electrochemiluminescence assay in 63 patients with gastric cancer and 71 patients with benign gastrosia. Results The levels of three kinds of tumor marker in gastric cancer group were obviously higher than those in benign gastrosia group (P〈0.01). The sensitivity of detection was improved when the combined detection of CEA, CA19-9 and CA72-4 (P〈0.05) was used. Conclusion The combined detection of CEA, CA19-9 and CA72-4 can significantly improve the sensitivity and specificity of diagnosis of gastric cancer.
作者 张辉
机构地区 南京市江宁医院
出处 《当代医学》 2009年第16期81-82,共2页 Contemporary Medicine
关键词 胃癌 CEA CA19-9 CA72-4 Gastric cancer CEA CA19-9 CA72-4
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